Q2.. Describe the components of extracellular matrix.
- ECM provides structural support, regulates cell behavior, and facilitates cell communication.
- Proteoglycans (core protein + GAGs) attract water, resist compression, and hydrate ECM.
- Collagen, a fibrous protein, provides tensile strength to tissues through triple helices.
- Elastin, another fibrous protein, grants elasticity and recoil to stretchable tissues.
Answer: The extracellular matrix (ECM) is a complex, dynamic network of secreted macromolecules that provides structural and biochemical support to surrounding cells. It plays a pivotal role in regulating cellular functions, tissue development, and repair. The ECM comprises three main classes of biomolecules: proteoglycans, fibrous proteins, and multi-adhesive glycoproteins, along with water and minerals. Proteoglycans are a crucial component, consisting of a core protein covalently attached to one or ...